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1

Deconstructing and targeting the genomic architecture of human neurodegeneration

De Jager, Philip L., Yang, Hyun-Sik, Bennett, David A

Journal:

Nature Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.27 MB

english, 2018

2

Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts

Allnutt, Mary Alice, Johnson, Kory, Bennett, David A., Connor, Sarah M., Troncoso, Juan C., Pletnikova, Olga, Albert, Marilyn S., Resnick, Susan M., Scholz, Sonja W., De Jager, Philip L., Jacobson, St

Journal:

Year:

2020

Language:

english

File:

PDF, 1.15 MB

english, 2020

3

Su.86. Automated High-dimensional Flow Cytometric Data Analysis

Xinli Hu, Saumyadipta Pyne, Elizabeth Rossin, Pablo Tamayo, David Hafler, Jill Mesirov, Philip De Jager

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

4

Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues

Zhu, Jiang, Adli, Mazhar, Zou, James Y., Verstappen, Griet, Coyne, Michael, Zhang, Xiaolan, Durham, Timothy, Miri, Mohammad, Deshpande, Vikram, De Jager, Philip L., Bennett, David A., Houmard, Joseph

Journal:

Year:

2013

Language:

english

File:

PDF, 2.54 MB

english, 2013

5

Charting a dynamic DNA methylation landscape of the human genome

Ziller, Michael J., Gu, Hongcang, Müller, Fabian, Donaghey, Julie, Tsai, Linus T.-Y., Kohlbacher, Oliver, De Jager, Philip L., Rosen, Evan D., Bennett, David A., Bernstein, Bradley E., Gnirke, Andreas

Journal:

Year:

2013

Language:

english

File:

PDF, 524 KB

english, 2013

6

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines

Choy, Edwin, Yelensky, Roman, Bonakdar, Sasha, Plenge, Robert M., Saxena, Richa, De Jager, Philip L., Shaw, Stanley Y., Wolfish, Cara S., Slavik, Jacqueline M., Cotsapas, Chris, Rivas, Manuel, Dermitz

Journal:

Year:

2008

Language:

english

File:

PDF, 736 KB

english, 2008

7

What is the epigenome and is it involved in multiple sclerosis?

Lee, Ji Y, De Jager, Philip L

Journal:

Multiple Sclerosis Journal

Year:

2018

Language:

english

File:

PDF, 46 KB

english, 2018

8

A Novel Landscape for Understanding Physical and Mental Health: Body Mapping Research with Youth Experiencing Psychosis

Boydell, Katherine M., Ball, Jeffrey, Curtis, Jackie, De Jager, Adèle, Kalucy, Megan, Lappin, Julia, Rosenbaum, Simon, Tewson, Anna, Vaughan, Priya, Ward, Philip B., Watkins, Andrew

Journal:

Art/Research International: A Transdisciplinary Journal

Year:

2018

File:

PDF, 823 KB

2018

9

A second major histocompatibility complex susceptibility locus for multiple sclerosis

Tai Wai Yeo, Philip L. De Jager, Simon G. Gregory, Lisa F. Barcellos, Amie Walton, An Goris, Chiara Fenoglio, Maria Ban, Craig J. Taylor, Reyna S. Goodman, Emily Walsh, Cara S. Wolfish, Roger Horton,

Journal:

Annals of Neurology

Year:

2007

Language:

english

File:

PDF, 99 KB

english, 2007

10

Uncovering the genetic architecture of white matter disease

Neelum T. Aggarwal, Philip L. De Jager

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 53 KB

english, 2011

11

Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: Increased t allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease

Hui Wu, Rita M. Cantor, Deborah S. Cunninghame Graham, Cecilia M. Lingren, Lisa Farwell, Philip L. De Jager, Nunzio Bottini, Jennifer M. Grossman, Daniel J. Wallace, Bevra H. Hahn, Heikki Julkunen, Le

Journal:

Arthritis & Rheumatism

Year:

2005

Language:

english

File:

PDF, 77 KB

english, 2005

12

Genetic variation in toll-like receptor 9 and susceptibility to systemic lupus erythematosus

Philip L. De Jager, Angela Richardson, Tim J. Vyse, John D. Rioux

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

13

Molecular imaging in neuroendocrine tumors: Molecular uptake mechanisms and clinical results

Klaas P. Koopmans, Oliver N. Neels, Ido P. Kema, Philip H. Elsinga, Thera P. Links, Elisabeth G.E. de Vries, Pieter L. Jager

Journal:

Critical Reviews in Oncology/Hematology

Year:

2009

Language:

english

File:

PDF, 1.70 MB

english, 2009

14

A new allele of the lurcher gene, lurcher

Philip L. De Jager, Jian Zuo, Susan A. Cook, Nathaniel Heintz

Journal:

Mammalian Genome

Year:

1997

Language:

english

File:

PDF, 1.56 MB

english, 1997

15

Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach

Benjamin Rhodes, David L. Morris, Lakshman Subrahmanyan, Cristin Aubin, Carlos F. Mendes de Leon, Jeremiah F. Kelly, Dennis A. Evans, John C. Whittaker, Jorge R. Oksenberg, Philip L. De Jager, Tim J.

Journal:

Year:

2008

Language:

english

File:

PDF, 663 KB

english, 2008

16

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility

Rebecca L. Zuvich, Jacob L. McCauley, Jorge R. Oksenberg, Stephen J. Sawcer, Philip L. De Jager, International Multiple Sclerosis Genetics Consortium, Cristin Aubin, Anne H. Cross, Laura Piccio, Neelu

Journal:

Year:

2010

Language:

english

File:

PDF, 219 KB

english, 2010

17

Multiple sclerosis

David A. Hafler, Jacqueline M. Slavik, David E. Anderson, Kevin C. O'Connor, Philip De Jager, Clare Baecher-Allan

Journal:

Immunological Reviews

Year:

2005

Language:

english

File:

PDF, 630 KB

english, 2005

18

GluRδ2 and the Development and Death of Cerebellar Purkinje Neurons in Lurcher Mice

Nathaniel Heintz, Philip L. De Jager

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 271 KB

english, 1999

19

The Lurcher Mutation and Ionotropic Glutamate Receptors: Contributions to Programmed Neuronal Death In vivo

Philip L. De Jager, Nathaniel Heintz

Journal:

Brain Pathology

Year:

1998

Language:

english

File:

PDF, 201 KB

english, 1998

20

10.1038/42009

Heintz, Nathaniel, Zuo, Jian, De Jager, Philip L., Takahashi, Kanji A., Jiang, Weining, Linden, David J.

Journal:

Year:

1997

Language:

english

File:

PDF, 344 KB

english, 1997

21

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

De Jager, Philip L, Jia, Xiaoming, Wang, Joanne, de Bakker, Paul I W, Ottoboni, Linda, Aggarwal, Neelum T, Piccio, Laura, Raychaudhuri, Soumya, Tran, Dong, Aubin, Cristin

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 385 KB

english, 2009

22

Evidence for a common pathway linking neurodegenerative diseases

Shulman, Joshua M, De Jager, Philip L

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 356 KB

english, 2009

23

A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility

Reich, David, Patterson, Nick, Jager, Philip L De, McDonald, Gavin J, Waliszewska, Alicja, Tandon, Arti, Lincoln, Robin R, DeLoa, Cari, Fruhan, Scott A, Cabre, Philippe

Journal:

Nature Genetics

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

24

Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

O'Connor, Kevin C, McLaughlin, Katherine A, De Jager, Philip L, Chitnis, Tanuja, Bettelli, Estelle, Xu, Chenqi, Robinson, William H, Cherry, Sunil V, Bar-Or, Amit, Banwell, Brenda

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 314 KB

english, 2007

25

Opinion: Applying a new generation of genetic maps to understand human inflammatory disease

Hafler, David A., Jager, Philip L. De

Journal:

Nature Reviews Immunology

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

26

Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis

De Jager, Philip L, Sawcer, Stephen, Waliszewska, Alicja, Farwell, Lisa, Wild, Gary, Cohen, Albert, Langelier, Diane, Bitton, Alain, Compston, Alastair, Hafler, David A

Journal:

European Journal of Human Genetics

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

27

Functional Screening of Alzheimer Pathology Genome-wide Association Signals in Drosophila

Joshua M. Shulman, Portia Chipendo, Lori B. Chibnik, Cristin Aubin, Dong Tran, Brendan T. Keenan, Patricia L. Kramer, Julie A. Schneider, David A. Bennett, Mel B. Feany, Philip L. De Jager

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 492 KB

english, 2011

28

Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection

Towfique Raj, Joshua M. Shulman, Brendan T. Keenan, Lori B. Chibnik, Denis A. Evans, David A. Bennett, Barbara E. Stranger, Philip L. De Jager

Journal:

The American Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 493 KB

english, 2012

29

OR.22. Dissection of the Admixture Multiple Sclerosis Susceptibility Locus On Chromosome 1 in An African-American Population

Philip De Jager, Nick Patterson, Gavin McDonald, Alicja Waliszewska, Bruce Cree, Chavie Wolfish, Steven Hauser, Jorge Oksenberg, David Reich, David Hafler

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

30

Sa.27. Genotype/Phenotype and Epistasis Analyses of Toll-Like Receptor Pathway Alleles Associated with Risk of Inflammatory Bowel Disease

Alicja Waliszewska, Philip De Jager, Denis Franchimont, David Hafler, John Rioux

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 43 KB

english, 2006

31

Sa.43. Role of the HLA DRB1*1501 Risk Haplotype in the Expression of Clinical and Radiographic Phenotypes of Multiple Sclerosis

Philip De Jager, Guttmann Charles, Chavie Wolfish, Christopher Holland, Tarik Alkasab, Alex Parker, Ronenn Roubenoff, Samia Khoury, David Hafler, Howard Weiner

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

32

An Association Between the Autoimmune Susceptibility Locus CTLA4 and Alterations in Proximal TCR Signaling in Healthy Human Volunteers

Lisa Maier, David Anderson, Philip de Jager, David Hafler, Linda Wicker

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

33

A Genome-wide Screen for Genetic Variants Affecting the Expression of Immunologically Relevant Cell Surface Markers

Philip De Jager, Roman Yelensky, Elizabeth Rossin, Sasha Bonadkar, Edwin Choy, Mark Daly, David Altshuler, David Hafler

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 42 KB

english, 2007

34

Novel Computational Methods to Enhance the Analysis of Cytometric Immunophenotypes

Philip De Jager, Saumyadipta Pyne, Elizabeth Rossin, Jill Mesirov, Pablo Tamayo, David Hafler

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 53 KB

english, 2007

35

Large Scale Immunoprofiling Uncovers Population Structure in Untreated MS Subjects and Highlights the Role of NK Cells

Elizabeth Rossin, Vissia Viglietta, Dulce Soler-Ferran, Alex Parker, Mira Weiner, Guy Buckle, Samia Khoury, David Hafler, Howard Weiner, Philip De Jager

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

36

OR.102. The CD58 Pathway is Implicated in MS Susceptibility

Philip De Jager, Clare Baecher-Allan, Lisa Maier, Stephen Sawcer, An Goris, Janna Saarela, Lisa Barcellos, Bénédicte Dubois, Leena Peltonen, Aarno Palotie, Howard Weiner, David Booth, Graeme Stewart,

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 58 KB

english, 2008

37

F.34. Changes in the CD8dimCD4- Cell Population Parallel Disease Activity in Treated Multiple Sclerosis Subjects

Philip De Jager, Pia Kivisäkk, Xinli Hu, Dulce Soler-Ferran, Elena Izmailova, Carmeline O'Brien, David Hafler, Howard Weiner, Samia Khoury

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

38

F.33. Genetic Variants that Control the Expression of MHC Genes Do Not Affect Susceptibility to Multiple Sclerosis

Linda Ottoboni, Erica Young, Roman Yelensky, David Hafler, Mark Daly, Philip De Jager

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

39

Sa.109. Allelic and Phenotypic Heterogeneity at the Autoimmune Susceptibility Locus IL2RA

Lisa Maier, Christopher Severson, Philip De Jager, David Hafler

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 43 KB

english, 2008

40

F.27. Meta-analysis of Genome Scans and Replication Identify CD6, ICSBP1, and TNFRSF1A as Novel Multiple Sclerosis Susceptibility Loci

Philip De Jager, Paul de Bakker, Joanne Wang, Linda Ottoboni, International MS Genetics Consortium, Stephen Hauser, Jorge Oksenberg, David Hafler

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

41

Population structure and HLA DRB1*1501 in the response of subjects with multiple sclerosis to first-line treatments

Robert Gross, Brian C. Healy, Sabine Cepok, Tanuja Chitnis, Samia J. Khoury, Bernard Hemmer, Howard L. Weiner, David A. Hafler, Philip L. De Jager

Journal:

Journal of Neuroimmunology

Year:

2011

Language:

english

File:

PDF, 631 KB

english, 2011

42

Exploring the role of the epigenome in multiple sclerosis: A window onto cell-specific transcriptional potential

Anna Kaliszewska, Philip L. De Jager

Journal:

Journal of Neuroimmunology

Year:

2012

Language:

english

File:

PDF, 451 KB

english, 2012

43

Gene expression profiling in MS: what is the clinical relevance?

Philip L De Jager, David A Hafler

Journal:

The Lancet Neurology

Year:

2004

Language:

english

File:

PDF, 49 KB

english, 2004

44

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

Philip L De Jager, Lori B Chibnik, Jing Cui, Joachim Reischl, Stephan Lehr, K Claire Simon, Cristin Aubin, David Bauer, Jürgen F Heubach, Rupert Sandbrink, Michaela Tyblova, Petra Lelkova, Eva Havrdov

Journal:

The Lancet Neurology

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

45

The CETP I405V polymorphism is associated with an increased risk of Alzheimer’s disease

Lei Yu, Joshua M. Shulman, Lori Chibnik, Sue Leurgans, Julie A. Schneider, Philip L. De Jager, David A. Bennett

Journal:

Year:

2012

Language:

english

File:

PDF, 130 KB

english, 2012

46

The Human Glutamate Receptor δ2 Gene (GRID2) Maps to Chromosome 4q22

Wei Hu, Jian Zuo, Philip L. De Jager, Nathaniel Heintz

Journal:

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

47

A High-Resolution Genetic Map of the Nervous Locus on Mouse Chromosome 8

Philip L De Jager, Diane Harvey, Alexandros D Polydorides, Jian Zuo, Nathaniel Heintz

Journal:

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

48

Diagnostic Performance of 123I-Labeled Serum Amyloid P Component Scintigraphy in Patients with Amyloidosis

Bouke P.C. Hazenberg, Martin H. van Rijswijk, D. Albertus Piers, Marjolijn N. Lub-de Hooge, Edo Vellenga, Elizabeth B. Haagsma, Philip N. Hawkins, Pieter L. Jager

Journal:

The American Journal of Medicine

Year:

2006

Language:

english

File:

PDF, 313 KB

english, 2006

49

Sa.137. Toll-Like Receptor Pathway Polymorphisms and Association to Inflammatory Bowel Disease

Philip De Jager, Denis Franchimont, Alicja Waliszewska, Alain Bitton, Albert Cohen, Jacques Belaiche, Diane Langelier, Lisa Farwell, An Goris, Cecile Libioulle, Niraj Jani, Themistocle Dassopoulos, Br

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 41 KB

english, 2006

50

A genome-wide scan for common variants affecting the rate of age-related cognitive decline

Philip L. De Jager, Joshua M. Shulman, Lori B. Chibnik, Brendan T. Keenan, Towfique Raj, Robert S. Wilson, Lei Yu, Sue E. Leurgans, Dong Tran, Cristin Aubin, Christopher D. Anderson, Alessandro Biffi,

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

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